Steroid Therapy in Asthma

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Steroid therapy in asthma.

In the following article the indications for the use of steroids in asthma are considered. The risks attendant upon such treatment are discussed. A comparison is made between the effects of the naturally occurring preparations and some of the modern synthetic analogues. The following table shows roughly equivalent doses of the various oral steroid preparations, so that comparable doses can read...

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Steroid Therapy in Asthma

In the following article the indications for the use of steroids in asthma are considered. The risks attendant upon such treatment are discussed. A comparison is made between the effects of the naturally occurring preparations and some of the modern synthetic analogues. The following table shows roughly equivalent doses of the various oral steroid preparations, so that comparable doses can read...

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Underuse of inhaled steroid therapy in elderly patients with asthma.

STUDY OBJECTIVES Despite their proven efficacy, inhaled steroids may be underused in the elderly asthmatic population. The objectives of this study were to determine if inhaled steroids are underused in the elderly asthmatic population, who are at a high risk for rehospitalization and mortality, and to identify certain risk factors that predict lower use of inhaled steroids in this group of pat...

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Effects of steroid therapy on inflammatory cell subtypes in asthma.

RATIONALE Airway inflammation in asthma is heterogeneous with different phenotypes. The inflammatory cell phenotype is modified by corticosteroids and smoking. Steroid therapy is beneficial in eosinophilic asthma (EA), but evidence is conflicting regarding non-eosinophilic asthma (NEA). OBJECTIVES To assess the inflammatory cell phenotypes in asthma after eliminating potentially confounding eff...

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Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma.

BACKGROUND Steroid-insensitive endotypes of asthma are an important clinical problem and effective therapies are required. They are associated with bacterial infection and non-eosinophilic inflammatory responses in the asthmatic lung. Macrolide therapy is effective in steroid-insensitive endotypes, such as non-eosinophilic asthma. However, whether the effects of macrolides are due to antimicrob...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1959

ISSN: 0032-5473

DOI: 10.1136/pgmj.35.406.463